Gatifloxacin USP RC E sodium CAS 1029364-65-5 (acid)
| CAS No. | 1029364-65-5 (acid) |
| Molecular Formula | C19H21FN3O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Gatifloxacin USP RC E sodium (CAS 1029364-65-5 (acid)) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21FN3O4Na and a molecular weight of 397.38 g/mol.
The molecular framework of Gatifloxacin USP RC E sodium (C19H21FN3O4Na) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H21FN3O4 Na |
| Molecular Weight | 397.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Gatifloxacin Standards
- Gatifloxacin USP RC E (CAS 1029364-65-5)
- Gatifloxacin Impurity 13 (CAS 103460-87-3)
- Gatifloxacin Impurity 4 (CAS 103460-89-5)
- Gatifloxacin Impurity 17 (CAS 1048972-28-6)
- Gatifloxacin Impurity 18 (CAS 1048972-69-5)
- Gatifloxacin Impurity 36 (CAS 1048972-69-5 (free base))
- Gatifloxacin Related Compound D(3-Desmethyl Gatifloxacin) (CAS 112811-57-1)
- Gatifloxacin Impurity 23 (CAS 112811-58-2)
Recommended Standards
- Desvenlafaxine USP Related Compound A (CAS 1346600-38-1)
- Papaverine Impurity 46 (CAS CATO-C4X-206746)
- Tapentadol EP Impurity E (CAS 175591-22-7)
- 4-Hydroxy-3-(3-methoxybenzoyl)benzoic Acid Methyl Ester (CAS 68595-46-0)
- Ethyl (R)-5-methyl-4-oxo-5-(trifluoromethyl)-4,5-dihydrofuran-2-carboxylate (CAS 2878423-90-4)
- Pretomanid Impurity 27 (CAS CATO-C4X-260627)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(trifluoromethyl)-1H-indole (CAS 1449581-09-2)
- 1,1-Dimethyl-2,3,4,9-tetrahydro-1h-pyrido[3,4-b]indole-3-carboxylic acid (CAS 73198-03-5)
- Isavuconazole Impurity 52 (CAS CATO-C4X-123652)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
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